SERVER

Pubchem MCP Server

Rank #1,529

io.github.cyanheads/pubchem-mcp-server

Search PubChem compounds, properties, safety data, bioactivity, and cross-references.

40 versions

9 GitHub stars

by cyanheads (154 servers)View repository ↗Claim this server

First listed

Jun 30, 2025

Last publish date

Oct 7, 2026

OVERVIEW

Pubchem MCP Server is a Model Context Protocol (MCP) server published by cyanheads. It ranks #1,529 of 143,385 servers tracked on MCP Toplist, and its repository has 9 GitHub stars. Pubchem MCP Server is listed across 3 registries — Official MCP, PulseMCP and Glama, with 40 tracked versions. It was first listed on Jun 30, 2025 and most recently updated on Oct 7, 2026.

STANDING

#1,529of 143,385 tracked serversTop 5%

Ranks ahead of 141,856 of 143,385 servers on MCP Toplist.

CONNECT

Use Pubchem MCP Server

No setupRuns out of the box

No credentials or required configuration declared — add it to your MCP client and go.

Remote · HTTP

claude mcp add --transport http pubchem-mcp-server https://pubchem.caseyjhand.com/mcp

npm package

claude mcp add pubchem-mcp-server -e "MCP_LOG_LEVEL=<your MCP_LOG_LEVEL>" -- npx -y @cyanheads/pubchem-mcp-server

Replace each placeholder with your own value before saving.

npm package

claude mcp add pubchem-mcp-server -e "MCP_TRANSPORT_TYPE=<your MCP_TRANSPORT_TYPE>" -e "MCP_SESSION_MODE=<your MCP_SESSION_MODE>" -e "MCP_HTTP_HOST=<your MCP_HTTP_HOST>" -e "MCP_HTTP_PORT=<your MCP_HTTP_PORT>" -e "MCP_HTTP_ENDPOINT_PATH=<your MCP_HTTP_ENDPOINT_PATH>" -e "MCP_AUTH_MODE=<your MCP_AUTH_MODE>" -e "MCP_LOG_LEVEL=<your MCP_LOG_LEVEL>" -- npx -y @cyanheads/pubchem-mcp-server

Replace each placeholder with your own value before saving.

Remote · HTTP

[mcp_servers.pubchem-mcp-server]
url = "https://pubchem.caseyjhand.com/mcp"

Add to ~/.codex/config.toml.

npm package

[mcp_servers.pubchem-mcp-server]
command = "npx"
args = ["-y", "@cyanheads/pubchem-mcp-server"]

[mcp_servers.pubchem-mcp-server.env]
MCP_LOG_LEVEL = "<your MCP_LOG_LEVEL>"

Add to ~/.codex/config.toml. Replace each placeholder with your own value before saving.

npm package

[mcp_servers.pubchem-mcp-server]
command = "npx"
args = ["-y", "@cyanheads/pubchem-mcp-server"]

[mcp_servers.pubchem-mcp-server.env]
MCP_TRANSPORT_TYPE = "<your MCP_TRANSPORT_TYPE>"
MCP_SESSION_MODE = "<your MCP_SESSION_MODE>"
MCP_HTTP_HOST = "<your MCP_HTTP_HOST>"
MCP_HTTP_PORT = "<your MCP_HTTP_PORT>"
MCP_HTTP_ENDPOINT_PATH = "<your MCP_HTTP_ENDPOINT_PATH>"
MCP_AUTH_MODE = "<your MCP_AUTH_MODE>"
MCP_LOG_LEVEL = "<your MCP_LOG_LEVEL>"

Add to ~/.codex/config.toml. Replace each placeholder with your own value before saving.

Remote · HTTP

https://pubchem.caseyjhand.com/mcp

Settings → Connectors → “Add custom connector”, then paste this URL.

npm package

{
  "mcpServers": {
    "pubchem-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/pubchem-mcp-server"
      ],
      "env": {
        "MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
      }
    }
  }
}

Add to claude_desktop_config.json (Settings → Developer → Edit Config). Replace each placeholder with your own value before saving.

npm package

{
  "mcpServers": {
    "pubchem-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/pubchem-mcp-server"
      ],
      "env": {
        "MCP_TRANSPORT_TYPE": "<your MCP_TRANSPORT_TYPE>",
        "MCP_SESSION_MODE": "<your MCP_SESSION_MODE>",
        "MCP_HTTP_HOST": "<your MCP_HTTP_HOST>",
        "MCP_HTTP_PORT": "<your MCP_HTTP_PORT>",
        "MCP_HTTP_ENDPOINT_PATH": "<your MCP_HTTP_ENDPOINT_PATH>",
        "MCP_AUTH_MODE": "<your MCP_AUTH_MODE>",
        "MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
      }
    }
  }
}

Add to claude_desktop_config.json (Settings → Developer → Edit Config). Replace each placeholder with your own value before saving.

Remote · HTTP

{
  "mcpServers": {
    "pubchem-mcp-server": {
      "url": "https://pubchem.caseyjhand.com/mcp"
    }
  }
}

Add to ~/.cursor/mcp.json (global) or .cursor/mcp.json (per project).

npm package

{
  "mcpServers": {
    "pubchem-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/pubchem-mcp-server"
      ],
      "env": {
        "MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
      }
    }
  }
}

Add to ~/.cursor/mcp.json (global) or .cursor/mcp.json (per project). Replace each placeholder with your own value before saving.

npm package

{
  "mcpServers": {
    "pubchem-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/pubchem-mcp-server"
      ],
      "env": {
        "MCP_TRANSPORT_TYPE": "<your MCP_TRANSPORT_TYPE>",
        "MCP_SESSION_MODE": "<your MCP_SESSION_MODE>",
        "MCP_HTTP_HOST": "<your MCP_HTTP_HOST>",
        "MCP_HTTP_PORT": "<your MCP_HTTP_PORT>",
        "MCP_HTTP_ENDPOINT_PATH": "<your MCP_HTTP_ENDPOINT_PATH>",
        "MCP_AUTH_MODE": "<your MCP_AUTH_MODE>",
        "MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
      }
    }
  }
}

Add to ~/.cursor/mcp.json (global) or .cursor/mcp.json (per project). Replace each placeholder with your own value before saving.

Remote · HTTP

{
  "servers": {
    "pubchem-mcp-server": {
      "type": "http",
      "url": "https://pubchem.caseyjhand.com/mcp"
    }
  }
}

Save as .vscode/mcp.json in your workspace.

npm package

{
  "servers": {
    "pubchem-mcp-server": {
      "type": "stdio",
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/pubchem-mcp-server"
      ],
      "env": {
        "MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
      }
    }
  }
}

Save as .vscode/mcp.json in your workspace. Replace each placeholder with your own value before saving.

npm package

{
  "servers": {
    "pubchem-mcp-server": {
      "type": "stdio",
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/pubchem-mcp-server"
      ],
      "env": {
        "MCP_TRANSPORT_TYPE": "<your MCP_TRANSPORT_TYPE>",
        "MCP_SESSION_MODE": "<your MCP_SESSION_MODE>",
        "MCP_HTTP_HOST": "<your MCP_HTTP_HOST>",
        "MCP_HTTP_PORT": "<your MCP_HTTP_PORT>",
        "MCP_HTTP_ENDPOINT_PATH": "<your MCP_HTTP_ENDPOINT_PATH>",
        "MCP_AUTH_MODE": "<your MCP_AUTH_MODE>",
        "MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
      }
    }
  }
}

Save as .vscode/mcp.json in your workspace. Replace each placeholder with your own value before saving.

Remote · HTTP

{
  "mcpServers": {
    "pubchem-mcp-server": {
      "serverUrl": "https://pubchem.caseyjhand.com/mcp"
    }
  }
}

Add to ~/.codeium/windsurf/mcp_config.json.

npm package

{
  "mcpServers": {
    "pubchem-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/pubchem-mcp-server"
      ],
      "env": {
        "MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
      }
    }
  }
}

Add to ~/.codeium/windsurf/mcp_config.json. Replace each placeholder with your own value before saving.

npm package

{
  "mcpServers": {
    "pubchem-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/pubchem-mcp-server"
      ],
      "env": {
        "MCP_TRANSPORT_TYPE": "<your MCP_TRANSPORT_TYPE>",
        "MCP_SESSION_MODE": "<your MCP_SESSION_MODE>",
        "MCP_HTTP_HOST": "<your MCP_HTTP_HOST>",
        "MCP_HTTP_PORT": "<your MCP_HTTP_PORT>",
        "MCP_HTTP_ENDPOINT_PATH": "<your MCP_HTTP_ENDPOINT_PATH>",
        "MCP_AUTH_MODE": "<your MCP_AUTH_MODE>",
        "MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
      }
    }
  }
}

Add to ~/.codeium/windsurf/mcp_config.json. Replace each placeholder with your own value before saving.

Remote · HTTP

{
  "mcpServers": {
    "pubchem-mcp-server": {
      "url": "https://pubchem.caseyjhand.com/mcp"
    }
  }
}

npm package

{
  "mcpServers": {
    "pubchem-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/pubchem-mcp-server"
      ],
      "env": {
        "MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
      }
    }
  }
}

Replace each placeholder with your own value before saving.

npm package

{
  "mcpServers": {
    "pubchem-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/pubchem-mcp-server"
      ],
      "env": {
        "MCP_TRANSPORT_TYPE": "<your MCP_TRANSPORT_TYPE>",
        "MCP_SESSION_MODE": "<your MCP_SESSION_MODE>",
        "MCP_HTTP_HOST": "<your MCP_HTTP_HOST>",
        "MCP_HTTP_PORT": "<your MCP_HTTP_PORT>",
        "MCP_HTTP_ENDPOINT_PATH": "<your MCP_HTTP_ENDPOINT_PATH>",
        "MCP_AUTH_MODE": "<your MCP_AUTH_MODE>",
        "MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
      }
    }
  }
}

Replace each placeholder with your own value before saving.

BADGE

Show your rank

Maintain this server? Add the live rank badge to your README — it updates automatically as the leaderboard changes.

Markdown

[![MCP Toplist](https://mcptoplist.com/badge/io.github.cyanheads%2Fpubchem-mcp-server.svg)](https://mcptoplist.com/server/io.github.cyanheads%2Fpubchem-mcp-server)

HTML

<a href="https://mcptoplist.com/server/io.github.cyanheads%2Fpubchem-mcp-server"><img src="https://mcptoplist.com/badge/io.github.cyanheads%2Fpubchem-mcp-server.svg" alt="MCP Toplist: Top 5% of 143,385" /></a>

Variants: append ?metric=score or ?metric=stars to the image URL.

REGISTRIES

Listed on 3 registries

Official MCP

PulseMCP

Glama

ORGANIZATION

cyanheads

Organization

cyanheads

Servers in org

154

Versions across org

2622

Other servers by cyanheads

View all cyanheads servers →

VERSIONS

Available versions (40)

Version	Published
0.6.6	Oct 7, 2026
0.6.5	Sep 25, 2026
0.6.4	Sep 25, 2026
0.6.3	Sep 19, 2026
0.6.2	Sep 13, 2026
0.6.1	Aug 21, 2026
0.6.0	Jul 28, 2026
0.5.2	Jul 28, 2026
0.5.1	Jul 28, 2026
0.5.0	Jul 28, 2026
0.4.3	Jul 28, 2026
0.4.2	Jul 28, 2026
0.4.1	Jul 3, 2026
0.4.0	Jul 3, 2026
0.3.1	Jul 3, 2026
0.3.0	Jun 30, 2026
0.2.4	Jun 20, 2026
0.2.3	Jun 13, 2026
0.2.2	Jun 2, 2026
0.2.1	Jun 2, 2026
0.2.0	Jun 2, 2026
0.1.23	Jun 2, 2026
0.1.22	May 30, 2026
0.1.21	May 29, 2026
0.1.20	May 23, 2026
0.1.19	May 16, 2026
0.1.18	May 5, 2026
0.1.17	May 1, 2026
0.1.16	Apr 24, 2026
0.1.14	Apr 19, 2026
0.1.13	Apr 19, 2026
0.1.12	Apr 19, 2026
0.1.11	Mar 30, 2026
0.1.10	Mar 28, 2026
0.1.9	Mar 28, 2026
0.1.8	Mar 23, 2026
0.1.6	Mar 22, 2026
0.1.4	Mar 22, 2026
0.1.3	Mar 21, 2026
0.1.0	Nov 25, 2024

FAQ

Frequently asked questions

Who maintains Pubchem MCP Server?: Pubchem MCP Server is maintained by cyanheads, which publishes 154 MCP servers (2622 total versions) tracked on MCP Toplist.
Is Pubchem MCP Server listed on the Official MCP Registry?: Yes — Pubchem MCP Server is listed on the Official MCP Registry, alongside PulseMCP and Glama.
How many versions does Pubchem MCP Server have?: MCP Toplist tracks 40 versions of Pubchem MCP Server, most recently published on Oct 7, 2026.
Where can I find the source code for Pubchem MCP Server?: The source code for Pubchem MCP Server is hosted at github.com/cyanheads/pubchem-mcp-server.

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