Pubchem MCP Server
Rank #2,178io.github.cyanheads/pubchem-mcp-server
Search PubChem compounds, properties, safety data, bioactivity, and cross-references.
Pubchem MCP Server is a Model Context Protocol (MCP) server published by cyanheads. It ranks #2,178 of 121,933 servers tracked on MCP Toplist, and its repository has 9 GitHub stars. Pubchem MCP Server is listed across 3 registries — Official MCP, PulseMCP and Glama, with 35 tracked versions. It was first listed on Jun 30, 2025 and most recently updated on Aug 21, 2026.
Ranks ahead of 119,755 of 121,933 servers on MCP Toplist.
Use Pubchem MCP Server
No credentials or required configuration declared — add it to your MCP client and go.
claude mcp add --transport http pubchem-mcp-server https://pubchem.caseyjhand.com/mcpclaude mcp add pubchem-mcp-server -e "MCP_LOG_LEVEL=<your MCP_LOG_LEVEL>" -- npx -y @cyanheads/pubchem-mcp-server run start:stdioReplace each placeholder with your own value before saving.
claude mcp add pubchem-mcp-server -e "MCP_HTTP_HOST=<your MCP_HTTP_HOST>" -e "MCP_HTTP_PORT=<your MCP_HTTP_PORT>" -e "MCP_HTTP_ENDPOINT_PATH=<your MCP_HTTP_ENDPOINT_PATH>" -e "MCP_AUTH_MODE=<your MCP_AUTH_MODE>" -e "MCP_LOG_LEVEL=<your MCP_LOG_LEVEL>" -- npx -y @cyanheads/pubchem-mcp-server run start:httpReplace each placeholder with your own value before saving.
[mcp_servers.pubchem-mcp-server]
url = "https://pubchem.caseyjhand.com/mcp"Add to ~/.codex/config.toml.
[mcp_servers.pubchem-mcp-server]
command = "npx"
args = ["-y", "@cyanheads/pubchem-mcp-server", "run", "start:stdio"]
[mcp_servers.pubchem-mcp-server.env]
MCP_LOG_LEVEL = "<your MCP_LOG_LEVEL>"Add to ~/.codex/config.toml. Replace each placeholder with your own value before saving.
[mcp_servers.pubchem-mcp-server]
command = "npx"
args = ["-y", "@cyanheads/pubchem-mcp-server", "run", "start:http"]
[mcp_servers.pubchem-mcp-server.env]
MCP_HTTP_HOST = "<your MCP_HTTP_HOST>"
MCP_HTTP_PORT = "<your MCP_HTTP_PORT>"
MCP_HTTP_ENDPOINT_PATH = "<your MCP_HTTP_ENDPOINT_PATH>"
MCP_AUTH_MODE = "<your MCP_AUTH_MODE>"
MCP_LOG_LEVEL = "<your MCP_LOG_LEVEL>"Add to ~/.codex/config.toml. Replace each placeholder with your own value before saving.
https://pubchem.caseyjhand.com/mcpSettings → Connectors → “Add custom connector”, then paste this URL.
{
"mcpServers": {
"pubchem-mcp-server": {
"command": "npx",
"args": [
"-y",
"@cyanheads/pubchem-mcp-server",
"run",
"start:stdio"
],
"env": {
"MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
}
}
}
}Add to claude_desktop_config.json (Settings → Developer → Edit Config). Replace each placeholder with your own value before saving.
{
"mcpServers": {
"pubchem-mcp-server": {
"command": "npx",
"args": [
"-y",
"@cyanheads/pubchem-mcp-server",
"run",
"start:http"
],
"env": {
"MCP_HTTP_HOST": "<your MCP_HTTP_HOST>",
"MCP_HTTP_PORT": "<your MCP_HTTP_PORT>",
"MCP_HTTP_ENDPOINT_PATH": "<your MCP_HTTP_ENDPOINT_PATH>",
"MCP_AUTH_MODE": "<your MCP_AUTH_MODE>",
"MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
}
}
}
}Add to claude_desktop_config.json (Settings → Developer → Edit Config). Replace each placeholder with your own value before saving.
{
"mcpServers": {
"pubchem-mcp-server": {
"url": "https://pubchem.caseyjhand.com/mcp"
}
}
}Add to ~/.cursor/mcp.json (global) or .cursor/mcp.json (per project).
{
"mcpServers": {
"pubchem-mcp-server": {
"command": "npx",
"args": [
"-y",
"@cyanheads/pubchem-mcp-server",
"run",
"start:stdio"
],
"env": {
"MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
}
}
}
}Add to ~/.cursor/mcp.json (global) or .cursor/mcp.json (per project). Replace each placeholder with your own value before saving.
{
"mcpServers": {
"pubchem-mcp-server": {
"command": "npx",
"args": [
"-y",
"@cyanheads/pubchem-mcp-server",
"run",
"start:http"
],
"env": {
"MCP_HTTP_HOST": "<your MCP_HTTP_HOST>",
"MCP_HTTP_PORT": "<your MCP_HTTP_PORT>",
"MCP_HTTP_ENDPOINT_PATH": "<your MCP_HTTP_ENDPOINT_PATH>",
"MCP_AUTH_MODE": "<your MCP_AUTH_MODE>",
"MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
}
}
}
}Add to ~/.cursor/mcp.json (global) or .cursor/mcp.json (per project). Replace each placeholder with your own value before saving.
{
"servers": {
"pubchem-mcp-server": {
"type": "http",
"url": "https://pubchem.caseyjhand.com/mcp"
}
}
}Save as .vscode/mcp.json in your workspace.
{
"servers": {
"pubchem-mcp-server": {
"type": "stdio",
"command": "npx",
"args": [
"-y",
"@cyanheads/pubchem-mcp-server",
"run",
"start:stdio"
],
"env": {
"MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
}
}
}
}Save as .vscode/mcp.json in your workspace. Replace each placeholder with your own value before saving.
{
"servers": {
"pubchem-mcp-server": {
"type": "stdio",
"command": "npx",
"args": [
"-y",
"@cyanheads/pubchem-mcp-server",
"run",
"start:http"
],
"env": {
"MCP_HTTP_HOST": "<your MCP_HTTP_HOST>",
"MCP_HTTP_PORT": "<your MCP_HTTP_PORT>",
"MCP_HTTP_ENDPOINT_PATH": "<your MCP_HTTP_ENDPOINT_PATH>",
"MCP_AUTH_MODE": "<your MCP_AUTH_MODE>",
"MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
}
}
}
}Save as .vscode/mcp.json in your workspace. Replace each placeholder with your own value before saving.
{
"mcpServers": {
"pubchem-mcp-server": {
"serverUrl": "https://pubchem.caseyjhand.com/mcp"
}
}
}Add to ~/.codeium/windsurf/mcp_config.json.
{
"mcpServers": {
"pubchem-mcp-server": {
"command": "npx",
"args": [
"-y",
"@cyanheads/pubchem-mcp-server",
"run",
"start:stdio"
],
"env": {
"MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
}
}
}
}Add to ~/.codeium/windsurf/mcp_config.json. Replace each placeholder with your own value before saving.
{
"mcpServers": {
"pubchem-mcp-server": {
"command": "npx",
"args": [
"-y",
"@cyanheads/pubchem-mcp-server",
"run",
"start:http"
],
"env": {
"MCP_HTTP_HOST": "<your MCP_HTTP_HOST>",
"MCP_HTTP_PORT": "<your MCP_HTTP_PORT>",
"MCP_HTTP_ENDPOINT_PATH": "<your MCP_HTTP_ENDPOINT_PATH>",
"MCP_AUTH_MODE": "<your MCP_AUTH_MODE>",
"MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
}
}
}
}Add to ~/.codeium/windsurf/mcp_config.json. Replace each placeholder with your own value before saving.
{
"mcpServers": {
"pubchem-mcp-server": {
"url": "https://pubchem.caseyjhand.com/mcp"
}
}
}{
"mcpServers": {
"pubchem-mcp-server": {
"command": "npx",
"args": [
"-y",
"@cyanheads/pubchem-mcp-server",
"run",
"start:stdio"
],
"env": {
"MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
}
}
}
}Replace each placeholder with your own value before saving.
{
"mcpServers": {
"pubchem-mcp-server": {
"command": "npx",
"args": [
"-y",
"@cyanheads/pubchem-mcp-server",
"run",
"start:http"
],
"env": {
"MCP_HTTP_HOST": "<your MCP_HTTP_HOST>",
"MCP_HTTP_PORT": "<your MCP_HTTP_PORT>",
"MCP_HTTP_ENDPOINT_PATH": "<your MCP_HTTP_ENDPOINT_PATH>",
"MCP_AUTH_MODE": "<your MCP_AUTH_MODE>",
"MCP_LOG_LEVEL": "<your MCP_LOG_LEVEL>"
}
}
}
}Replace each placeholder with your own value before saving.
Show your rank
Maintain this server? Add the live rank badge to your README — it updates automatically as the leaderboard changes.
[](https://mcptoplist.com/server/io.github.cyanheads%2Fpubchem-mcp-server)<a href="https://mcptoplist.com/server/io.github.cyanheads%2Fpubchem-mcp-server"><img src="https://mcptoplist.com/badge/io.github.cyanheads%2Fpubchem-mcp-server.svg" alt="MCP Toplist: Top 5% of 121,933" /></a>Variants: append ?metric=score or ?metric=stars to the image URL.
Listed on 3 registries
cyanheads
Other servers by cyanheads
- MCP Ts Core#72 · 184 vers
- obsidian-mcp-server#196 · 31 vers
- Pubmed MCP Server#341 · 78 vers
- Clinicaltrialsgov MCP Server#365 · 66 vers
- Git MCP Server#412 · 43 vers
- Openalex MCP Server#1,733 · 43 vers
- Secedgar MCP Server#1,803 · 52 vers
- ntfy-mcp-server#2,235 · 10 vers
- @cyanheads/openstreetmap-mcp-server#2,467 · 33 vers
- cdc-health-mcp-server#2,505 · 26 vers
- toolkit-mcp-server#2,508 · 6 vers
- Protein MCP Server#2,663 · 19 vers
Available versions (35)
| Version | Published |
|---|---|
| 0.6.1 | Aug 21, 2026 |
| 0.6.0 | Jul 28, 2026 |
| 0.5.2 | Jul 28, 2026 |
| 0.5.1 | Jul 28, 2026 |
| 0.5.0 | Jul 28, 2026 |
| 0.4.3 | Jul 28, 2026 |
| 0.4.2 | Jul 28, 2026 |
| 0.4.1 | Jul 3, 2026 |
| 0.4.0 | Jul 3, 2026 |
| 0.3.1 | Jul 3, 2026 |
| 0.3.0 | Jun 30, 2026 |
| 0.2.4 | Jun 20, 2026 |
| 0.2.3 | Jun 13, 2026 |
| 0.2.2 | Jun 2, 2026 |
| 0.2.1 | Jun 2, 2026 |
| 0.2.0 | Jun 2, 2026 |
| 0.1.23 | Jun 2, 2026 |
| 0.1.22 | May 30, 2026 |
| 0.1.21 | May 29, 2026 |
| 0.1.20 | May 23, 2026 |
| 0.1.19 | May 16, 2026 |
| 0.1.18 | May 5, 2026 |
| 0.1.17 | May 1, 2026 |
| 0.1.16 | Apr 24, 2026 |
| 0.1.14 | Apr 19, 2026 |
| 0.1.13 | Apr 19, 2026 |
| 0.1.12 | Apr 19, 2026 |
| 0.1.11 | Mar 30, 2026 |
| 0.1.10 | Mar 28, 2026 |
| 0.1.9 | Mar 28, 2026 |
| 0.1.8 | Mar 23, 2026 |
| 0.1.6 | Mar 22, 2026 |
| 0.1.4 | Mar 22, 2026 |
| 0.1.3 | Mar 21, 2026 |
| 0.1.0 | Nov 25, 2024 |
Frequently asked questions
- Who maintains Pubchem MCP Server?
- Pubchem MCP Server is maintained by cyanheads, which publishes 131 MCP servers (2112 total versions) tracked on MCP Toplist.
- Is Pubchem MCP Server listed on the Official MCP Registry?
- Yes — Pubchem MCP Server is listed on the Official MCP Registry, alongside PulseMCP and Glama.
- How many versions does Pubchem MCP Server have?
- MCP Toplist tracks 35 versions of Pubchem MCP Server, most recently published on Aug 21, 2026.
- Where can I find the source code for Pubchem MCP Server?
- The source code for Pubchem MCP Server is hosted at github.com/cyanheads/pubchem-mcp-server.
Do you run this server?
Community projects list the MCP servers behind real agents and apps. Publish yours and this page will link to it.