SERVER

Reactome

Rank #27,282

io.github.pipeworx-io/reactome

Reactome MCP — open biological pathway knowledge-base.

First listed
May 14, 2026
Last publish date
Sep 26, 2026
PURPOSE

What you can do with Reactome

Reactome is a Model Context Protocol (MCP) server published by pipeworx-io. It ranks #27,282 of 144,396 active servers on MCP Toplist. Reactome is listed across 3 registries — Official MCP, PulseMCP and Glama, with 3 tracked versions. It was first listed on May 14, 2026 and most recently updated on Sep 26, 2026.

Not verifiedMCP Toplist has not yet written a checked profile for this server, so the paragraph above is assembled from registry data only. The repository README is the authority on what it does.

CAPABILITIES AND LIMITATIONS

What Reactome can and cannot do

MCP Toplist connected to the public endpoint on Aug 28, 2026 and it listed 36 tools. Tool names are not stored, so what they do is not catalogued here.

Not verifiedMCP Toplist has not catalogued this server's tools or limitations. The repository README lists them.

REQUIREMENTS

What you need before using Reactome

VerifiedNo credentialsNo credentials declared

The registry listing declares no required environment variables or authentication. This is declared metadata, not a verified install — the repository README is the authority.

Verified by MCP Toplist on Aug 28, 2026: the public endpoint completed the MCP handshake and listed 36 tools without credentials.

Declared by Glama, last synced Oct 16, 2026. Not independently verified by MCP Toplist.

Declared in the registry install config

Hosted endpoint declared as public.

INSTALLATION AND FIRST TASK

Connect Reactome and confirm it works

Remote · HTTP
claude mcp add --transport http reactome https://gateway.pipeworx.io/reactome/mcp
First successful task

After adding the config, ask your client to list this server's tools. A tool list confirms the connection; an empty list or an error means the server did not start or needs credentials.

ALTERNATIVES

When to choose another server

Other servers by pipeworx-io
View all pipeworx-io servers →

No task-specific alternatives are catalogued for Reactomeyet; the list above is its publisher's other servers.

MAINTENANCE AND EVIDENCE

What changed, and when this was checked

First listed
May 14, 2026
Latest version published
Sep 26, 2026
Version history
3 versions tracked (below)
Requirements evidence
Verified by MCP Toplist on Aug 28, 2026: the public endpoint completed the MCP handshake and listed 36 tools without credentials.
Profile checked
Not yet — purpose, capabilities and requirements above come from registry data only
Ranking data as of
Oct 16, 2026
Registry sightings

Do you maintain Reactome? to correct or enrich this profile.

VERSIONS

Available versions (3)

0.1.0 · May 14, 20260.1.1 · Sep 25, 20260.1.2 · Sep 26, 2026May 14, 2026Sep 26, 2026
VersionPublished
0.1.2Sep 26, 2026
0.1.1Sep 25, 2026
0.1.0May 14, 2026
STANDING
#27,282of 144,396 active serversTop 25%

Ranks ahead of 117,114 of 144,396 servers on MCP Toplist.

BADGE

Show your rank

Maintain this server? Add the live rank badge to your README — it updates automatically as the leaderboard changes.

MCP Toplist: Top 25% of 144,396
Markdown
[![MCP Toplist](https://mcptoplist.com/badge/io.github.pipeworx-io%2Freactome.svg)](https://mcptoplist.com/server/io.github.pipeworx-io%2Freactome)
HTML
<a href="https://mcptoplist.com/server/io.github.pipeworx-io%2Freactome"><img src="https://mcptoplist.com/badge/io.github.pipeworx-io%2Freactome.svg" alt="MCP Toplist: Top 25% of 144,396" /></a>

Variants: append ?metric=score or ?metric=stars to the image URL.

FAQ

Frequently asked questions

Who maintains Reactome?
Reactome is maintained by pipeworx-io, which publishes 1832 MCP servers (5344 total versions) tracked on MCP Toplist.
Is Reactome listed on the Official MCP Registry?
Yes — Reactome is listed on the Official MCP Registry, alongside PulseMCP and Glama.
How many versions does Reactome have?
MCP Toplist tracks 3 versions of Reactome, most recently published on Sep 26, 2026.
Where can I find the source code for Reactome?
The source code for Reactome is hosted at github.com/pipeworx-io/mcp-reactome.
Used in projects

Do you run this server?

Community projects list the MCP servers behind real agents and apps. Publish yours and this page will link to it.

EXPLORE